Brandon Rios vs. Mike Alvarado (2nd meeting)
2013-03-30 : Brandon Rios 140 lbs lost to Mike Alvarado 140 lbs by UD in round 12 of 12
- Location: Mandalay Bay Resort & Casino, Las Vegas, Nevada, USA
- Referee: Tony Weeks
- Judge: Dave Moretti 113-115
- Judge: Bill Lerch 113-115
- Judge: Duane Ford 113-114
- Ring Announcer: Michael Buffer
- Aired On: HBO Boxing After Dark (Main Event)
- 2nd Weigh-In: Rios 161 lbs., Alvarado 158 lbs.
- interim WBO Light Welterweight Title
- Brandon Rios 31-0 (23 KOs) vs. Mike Alvarado 33-1 (23 KOs)
- Rios entered as the #6 jr. welterweight contender in the world according to The Ring Magazine. Alvarado, a 3.5-to-1 betting underdog, was ranked as the #8 contender by the same publication.  
- The purses for the bout were reported as Rios $1.25M, Alvarado $625K. 
- While in training, Alvarado suffered several cuts to his face and neck from what was speculated to be the result of a bar fight in which Alvarado was struck with a beer bottle.
- HBO's Harold Lederman scored the fight 116-112 in favor of Alvarado.
- Among those in attendance were Mike Tyson, Juan Manuel Marquez, Andre Ward, Timothy Bradley, Nonito Donaire, and Mikey Garcia.
A cut opened over the right eye of Alvarado in the opening round. In Round 2, Alvarado was staggered by jab and was caught again later in the round. The two traded power shots to close the second round. A right hand from Alvarado hurt Rios in the last minute of the third round. Action was paused in the fifth to allow Alvardo time to recover from a low blow. By the end of the fifth, Alvarado's face was swollen and marked. Alvarado utilized more movement in the second half of the fight and each man had his moments landing with solid power punches. A large cut opened to Alvarado's left eye in the final round and by the end of the fight he had significant swelling and bruising to both eyes. Rios had swelling and slight brusing to his left eye.
- "What a fight, son. This is what boxing needs. These are the guys they make movies about." - Roy Jones Jr.
- Following the fight both men indicated they would like to fight a third time, the next time being in Denver, Colorado, Alvarado's hometown.