Daniel Santos vs. Antonio Margarito (1st meeting)
2001-07-21 : Antonio Margarito 146 lbs fought without result Daniel Santos 147 lbs by NC at 2:11 in round 1 of 12
- Location: Coliseo Ruben Rodriguez, Bayamon, Puerto Rico
- Referee: Jose Hiram Rivera
- Judge: Adelaide Triplett
- Judge: Larry Hazzard Jr.
- Judge: Nelson Vazquez
- World Boxing Organization Welterweight Title
- Time: 2:11
- Weights: Margarito 146 lbs, Santos 147 lbs
- Promoter: Sports Network
- Ringside doctor stops bout at 2:11 after accidental headbutt causes bad cut to Margarito's right eye.