1942-12-11 : Tami Mauriello 183¾ lbs beat Lou Nova 203¾ lbs by KO at 2:43 in round 6 of 10
- Location: Madison Square Garden, New York, New York, USA
- Referee: Billy Cavanaugh
- Attendance: 15,369
Mauriello was knocked down for a nine count in the 1st round. Nova seemed to be doing well until he was KO'd in the 6th round, suffering a broken rib and torn cartilage in the bout.
By virtue of this win, Mauriello moved closer to the title of "Interim Heavyweight Champion," as reigning champion Joe Louis was currently serving in the United States military.