Manny Pacquiao vs. Juan Manuel Marquez (4th meeting)
2012-12-08 : Manny Pacquiao 147 lbs lost to Juan Manuel Marquez 143 lbs by KO at 2:59 in round 6 of 12
- Location: MGM Grand, Grand Garden Arena, Las Vegas, Nevada, USA
- Referee: Kenny Bayless
- Judge: Adalaide Byrd 47-46
- Judge: Steve Weisfeld 47-46
- Judge: John Keane 47-46
Marquez down in 5th round. Pacquiao down in 3rd round and down in the 5th round on a overhand right. The referee waved the count off. Billed as the WBO "Fighter of the Decade".