Not sure what your plans are in Vegas besides GingerHead v Khan, but I spend a relatively significant amount of time there. If you don't mind me asking, why are you thinking the Nobu? Nothing against it but it is rather posh and there are several good options. If you are going posh, I would consider The Cromwell. It also has one of the best club and pool scenes in Vegas.
Remember that if you are staying at any of the Caesars properties you can use your key to get into any pool on any Caesars property. Don't overlook the pool scenes at The Flamingo and the Linq.
The Marquee at The Cosmopolitan is another excellent nightclub. Hyde and The Bank at The Bellagio are also top end.
If you want Italian food you should catch a ride (taxi, limo, lyft, uber) to either Nora's or Ferraro's. They are family owned and operated by Italian families. Yes, you may find yourself sitting next to authentic, modern day gangsters. Most importantly, the food is superior. I took ten of my associates to Ferraro's two weeks ago. We had a private enclave. It was absolutely excellent, although my selection of reds was not up to my best efforts.
http://www.norascuisine.com/www/
http://www.ferraroslasvegas.com/
On the transportation subject. You need to develop a positive relationship with your hotel valets. If you do it right, they will get you limos for about the same price as taxis. Always negotiate the deal for a limo prior to getting in. The valet can often negotiate it or inform you of the optimum price available.
Uber and Lyft do operate in Vegas. I prefer Lyft. There are innate disadvantages with the shared ride scene in Vegas. Often it takes longer to get them to your location. Vegas is gamed in the direction of taxis and limos. The shared ride scene competition has seriously affected the price of limos though, in a positive direction for the consumer.
If a Lyft is available, they are generally about half of the price of a taxi. A Lyft from the airport to your hotel is an excellent option. There is a queue of Lyfts (and Ubers) waiting at the airport and it is half the price of a taxi or a limo. It is usually quicker than waiting in the taxi queue, btw.
Skip the hotel shuttles. They save you nothing and they take far longer.
Do not miss The Fremont Street Experience. That is where the real people hang and have fun. It is impossible to fully describe it but everything is more reasonably priced there. A few of the very best steakhouses are there (Hugo's Cellar in the basement of the Four Queens is my favorite). Your gambling odds are superior to the strip. There is a ton of free entertainment.
If I were you I would stay at The Golden Nugget on Fremont, or The Downtown Grand. They aren't so posh but if you are looking to party and have your money stretch farther downtown is the place to headquarter. The Strip is a short Lyft or Limo away.
Gordie Brown puts on an excellent show (impressionist) at the Nugget (which brings up tickets). There are tix4tonight booths with up to half priced tickets on a lot of shows on The Strip. The most convenient is on the southeast corner of The Strip (Las Vegas Blvd) and Flamingo (the absolute epicenter of The Strip). You should check there for show and tour tickets first thing.
What would you like to know about (or do in) Vegas?
he gave Murata a tough scrap was a great experience and hopefully we get another crack at a big fight stateside