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- Castillo is the younger brother of heavyweight boxer Elieser Castillo.
- Eliseo Castillo's boxing business advisor is his sister-in-law Karla Guadamuz-Castillo.
- She also serves as Manager for her husband and older brother of Eliseo - Cuban southpaw Elieser Castillo.
- The Castillo Boxing website is: www.castilloboxing.com